Mycotic Mastitis in Ruminants

Yanuartono Yanuartono, Alfarisa Nururrozi, Soedarmanto Indarjulianto, Slamet Raharjo, Hary Purnamaningsih


Mastitis is a disease caused by a wide variety of microorganisms that causes large economical loses and damages to the dairy industry by decreasing milk production and through increasing costs of antibiotic treatment and culling. In spite of the prevalence of mycotic mastitis is usually very low as compared to other agents of mastitis, but it has significantly increased during the last decade In recent years, fungal agents have been frequently reported among the causative agents for mastitis. Though moulds and yeasts are widely distributed in nature, only the yeasts are usually implicated as the cause of mycotic mastitis infections in ruminants. Given the importance of the disease, especially in terms of economic losses, in this short article we try to make a review to help practitioners and farmers in controlling and minimizing the incidence of mycotic mastitis.


mastitis; fungal; moulds; yeast; intra mammae

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Aalbaek, B., Stenderup, J., Jensen, H. E., Valbak, J., Nylin, B., and Huda, A. 1994. Mycotic and algal bovine mastitis in Denmark. APMIS, 102(6), 451-456, 10.1111/j.1699-0463.1994.tb04898 .x

Abd El-Khalek, H.M. 2017. Studies on mycotic mastitis in Egyptian buffa-loes with special reference to geno-typing for the most prevalent fungi. Animal Health Research Journal, 5 (1), 139-145, ISSN: 2356-7767

Abd El-Razik, K.A., Abdelrahman, K.A., Abd El-Moez, S.I., and Danial, E.N. 2011. New approach in diag-nosis and treatment of Bovine Mycotic Mastitis in Egypt. African Journal of Microbiology Research, 5(31), 5725 – 5732, DOI: 10.5897/ AJMR11.1200

Abdel-Rady, A., and Sayed, M. 2009. Epi-demiological Studies on Subclinical Mastitis in Dairy Cows in Assiut Governorate. Veterinary World, 2 (10), 373 – 380, doi: 10.5455/vet world.2009.373-380

Ahmad, R, Z., dan Gholib, D. 2016. Masti-tis Mikotik Akibat Terinfeksi Can-dida spp dan Trichosporon spp pada Peternakan Sapi Perah di Bo-gor, Bandung, dan Jakarta. Jurnal Veteriner, 17(1), 119-125, DOI: 10.19087/jveteriner.2016.17.1.119

Ahmad, R.Z. 2011. Mastitis Mikotik di In-donesia. Seminar Nasional Teknologi Peternakan dan Veteriner (pp, 403-410), Bogor - Indonesia.

Akdouche, L., Aissi, M., and Saadi, A. 2018. Prevalence and Identification of Yeasts Responsible for Mastitis in Dairy Cattle Farms in the Sidi Lahcene Region in the Wilaya of Sidi Bel abbes- Algeria. Journal Adv. Dairy Research, 6(2), 206. doi:10.4172/2329-888X.1000206

Akdouche, L., Aissi, M., Zenia, S., and Saadi, A. 2014. Importance of Yeasts in the Mammary Infection of the Cattle in the Region of Sidi M’Hamed Ben Ali, Wilaya of Relizane, Algeria. Journal Veterinar Science Technology, 5(2), 1-4.

Al–Kubaysi, S. M. A. 2008. Clinical and subclinical mycotic mastitis and the sensitivity and specificity of Cali-fornia Mastitis Test for diagnosis of subclinical mastitis in ewes in Al – Fallouja city. Al Qadisiyah Journal of Veterinary Medicine, 8(2), 34-45 DOI:10.13140/RG.2.2.32277.63204

Al-Doory Y. 1980. Laboratory Medical Mycology. Philadelphia USA. Lea & Febiger.

Aprilia, P.R., Santoso, S.A.B., dan Harjanti, D.W. 2016. Jumlah Staphylococcus aureus dan kandungan nutrien susu akibat dip-ping puting menggunakan ekstrak daun belimbing wuluh (Averrhoa bilimbi Linn) pada sapi perah penderita mastitis subklinis. Jurnal Ilmu-Ilmu Peternakan, 26(1), 43 – 51, DOI: ub.jiip.2016.026.01.7

Atef, H. A., El-Mokhtar, N. M., and Khalek, H. M. A. 2016. Compara-tive Effect of Ozone and Tradition-al Antimycotic Drugs on the Growth of Some Fungal Causes of Recurrent Mastitis in Egyptian Buf-faloes. Int. Journal of Curr. Microbiol. App. Sci., 5(12), 819-834. DOI: 6/ijcmas.2016.512.091

Bakr, E.M., Abd El-Tawab, A.E.M., Elshemey, T.M., and Abd- Elrhman, A.H. 2015. Diagnostic and Therapeutic Studies on Mycotic Mastitis in Cattle. Alexandria Journal of Veterinary Sciences, 46, 138-145. DOI: 10.5455/ajvs. 189682

Barnett, J.A., Payne, R.W., and Yarrow, D. 1983. Yeasts characteristics and identification, New York: Cam-bridge University Press.

Bassiri-Jahromi, S., Pourshafie, M.R., Ardakani, M. E., Ehsani, A.H., Doostkam, A., Katirae, F., and Mostafavi, E. 2018. In Vivo Com-parative Evaluation of the Pome-granate (Punica granatum) Peel Ex-tract as an Alternative Agent to Nystatin against Oral Candidiasis. Iran J. Med. Sci., 43(3), 296-304.

Bergonier, D., De Cremoux, R., Rupp, R., Lagriffoul, G., and Berthelot, X. 2003. Mastitis of dairy small rumi-nants. Vet. Res., 34(5), 689-716. DOI:10.1051/vetres:2003030

Blowey, R., and Edmondson, P. 2010. Mastitis control in dairy herds, 2nd edition., CAB international, Cam-bridge, MA, 02139, USA, 55

Boonyayatra, S., Tharavichitkul, P., and Oliver, S.P. 2018. Virulence-associated genes and molecular typ-ing of Streptococcus uberis associ-ated with bovine mastitis in north-ern Thailand. Turkish J. Vet. Anim. Sci., 42(1), 73-81, doi:10.3906/vet-1704-75

Bourabah, A., Ayad, A., Boukraa, L., Hammoudi, S.M., and Benbarek, H. 2013. Prevalence and Etiology of Subclinical Mastitis in Goats of the Tiaret Region, Algeria. Global Veterinaria, 11(5), 604-608, DOI: 10.5829/idosi.gv.2013.11.5.8112

Bourtzi-Hatzopoulou, E., Zdragas, A., Petridou, E., and Filiousis, G. 2003. Yeasts as a causative agent of bo-vine mastitis in Greece. Journal of the Hellenic Veterinary Medical Society 54(2), 105-110.


Bradley, A.J. 2002. Bovine Mastitis: An Evolving Disease. The Veterinary Journal, 164(2), 116-128.

Chahota, R., Katoch, R., Mahajan, A., and Verma, S. 2001. Clinical bovine mastitis caused by Geotrichum candidum. Vet. Arhiv., 71(4), 197-201.

Contreras, A., Sierra, D., Sanchez, A., Cor-rales, J.C., Marcoc, P.C., Paape, M.J., and Gonzalo, C. 2007. Masti-tis in small ruminants. Small Rum. Res., 68(1-2), 145-153.

Corti, S., Sicher, D., Regli, W., and Steph-an, R. 2003. Current data on antibi-otic resistance of the most im-portant bovine mastitis pathogens in Switzerland. Schweiz Archiv. Tierheilkd, 145(12), 571-575.


Costa, G.M., Pereira, U., Souza-Dias, M.A.G., and Silva, N. 2012. Yeast mastitis outbreak in a Brazilian dairy herd. Braz. J. Vet. Res. Anim. Sci. São Paulo, 49(3), 239-243.


Dalanezi, F.M., Souza da Paz, G., Joaquim,S.F., Guimarães, F.F., Bosco, S.M.G., and Helio Langoni, H. 2018. Short communication: The first report of Cyberlindnera rhodanensis associated with clinical bovine mastitis. J. Dairy Sci. 101(1), 581-583.

Davis, S.R. 2005. An overview of the anti-fungal properties of allicin and its breakdown products--the possibility of a safe and effective antifungal prophylactic. Mycoses, 48(2), 95-100.


Dubie, T., Sisay, T., Gebru, M., and Muktar, Y. 2015. An Insight Re-view on the Role of Fungi in Masti-tis of Dairy Animals and Its Eco-nomical Importance. The Journal of Veterinary Science, Photon 116, 440-445.

Dworecka-Kaszak, B., Alicja Krutkiewicz, A., Szopa, D., Kleczkowski, M., and Bieganska, M. 2012. High Prevalence of Candida Yeast in Milk Samples from Cows Suffering from Mastitis in Poland. The Scien-tific World Journal. 1-5. doi:10.1100/2012/196347

Ekin, I.H., Gurturk, K., Ilhan, Z., Arabaci, C., and Gulaydın, O. 2015. Detec-tion of enzyme activities and their relation to serotypes of bovine and human group B Streptococci. J. Med. Microbiol, 64(9), 985-989. DOI 10.1099/jmm.0.000124

Eldesouky, I., Mohamed, N., Khalaf, D., Salama, A., Elsify, A., Ombarak, R., El-Ballal, S., Effat, M., and Al Shabrawy, M. 2016. Candida Mas-titis in Dairy Cattle with Molecular Detection of Candida albicans. Kafkas Univ Vet Fak Derg, 22(3): 461-464

DOI: 10.9775/kvfd.2015.14843

Erbaş, G., Parin, U., Kirkan, S., Savaşan, S., Özavci, M.V., and Yüksel, H.T. 2017. Identification of Candida strains with nested PCR in bovine mastitis and determination of anti-fungal susceptibilities. Turk J Vet Anim Sci., 41, 757-763


Galfi, A.L., Radinović, M.Z., Davidov, I.N., Erdeljan, M.M., and Kovačević, Z.R. 2017. Detection of subclinical mastitis in dairy cows using California and Draminski mastitis test. Biotechnology in Ani-mal Husbandry, 33(4): 465-473.

Ghodasara, S.N., and Gajbhiye, P.U. 2015. Clinical Bovine Fungal Mastitis in Organized Dairy Farm, Molecular Microbiology Research, 5(5), 1-3.

doi: 10.5376/mmr.2015.05.0005

Godden, S., Rapnicki, P., Stewart, S., Fetrow, J., Johnson, A., Bey R., and Farnsworth, R. 2003. Effectiveness of an internal teat seal in the prevention of new intramammary infections during the dry and early-lactation periods in dairy cows when used with a dry cow intramammary antibiotic. J. Dairy Sci., 86(12), 3899-3911.


Gonzalez, R.N. 1996. Prototheca, Yeast, and Bacillus as a Cause of Mastitis. National Mastitis Council Annual Meeting, (pp. 82-89), Nashville, TN, USA..

Grzesiak, B., Kołodziej, B., Głowacka, A., and Krukowski, H. 2018. The Ef-fect of Some Natural Essential Oils Against Bovine Mastitis Caused by Prototheca zopfii Isolates In Vitro. Mycopathologia, 183, 541-550

Guler, L., Gunduz, K., Gulcu, Y., and Hadimli, H. H. 2005. Antimicrobial susceptibility and coagulase gene typing of Staphylococcus aureus isolated from bovine clinical masti-tis cases in Turkey. J. Dairy Sci., 88(9), 3149-3154.


Gunes, I., Kalkanci, A., and Kustimur, S. 2001. Comparison of Three Differ-ent Commercial Kits with Conven-tional Methods for the Identifica-tion of Candida Strains to Species Level. Bull Microbiol., 35, 559-564

Hakim, A.S., Abuelnaga, A.S.M., and Sayed El Ahl, R.M.H. 2013. Isola-tion, Biochemical Identification and Molecular Detection of Yeasts from Kareish Cheese. International Journal of Microbiological Re-search, 4(1), 95-100.


Hamadani, H., Khan, A.A., Banday, M.T., Ashraf, I., Handoo, N., Bashir, A., and Hamadani. A. 2013. Bovine Mastitis - A Disease of Serious Concern for Dairy Farmers. Inter-national Journal of Livestock Re-search, 3(1), 42-55. ISSN 2277-1964.

Hashim, A.J., Al-Kazaz, A.A., and Abdulmalek, H.W. 2013. PCR de-tection of Aspergillus flavus isolates for aflatoxin B1 producer. Journal of Biotechnology Research Center, 7(3), 81-89.

Hassan, B.H., Kshash, Q.H., and Offi , S.Y. 2014. Mycotic mastitis in sheep. Al-Qadisiya Journal of Vet. Med. Sci., 13(2), 1-4

Hastiono, S., Gholib, D., Zahari, P., dan Natalia, L. 1982. Mastitis mikotik pada sapi perah penelitian pendahuluan. Proceedings Pertemuan Ilmiah Ruminansia Besar, Balai Penelitian Veteriner, (pp.193–201), Bogor, Indonesia.

Hayashi, T., Sugita, T., Hata, E., Katsuda, K., Zhang, E., Yoshio Kiku, Y., Sugawara, K., Ozawa, T., Matsub-ara, T., Ando, T., Obayashi, T., Ito, T., Yabusaki, T., Kudo, K., Yama-moto, H., Koiwa, M., Oshida, T., Tagawa, Y., and Kawai, K. 2013. Molecular-Based Identification of Yeasts Isolated from Bovine Clini-cal Mastitis in Japan. J. Vet. Med. Sci., 75(3), 387–390.

doi: 10.1292/jvms.12-0362

Herrero, A.D., Ruiz, S.S., Bustillo, M.G., and Morales, P.C. 2006. Study of airborne fungal spores in Madrid, Spain. Aerobiologia, 22(2), 133–140. DOI 10.1007/s10453-006-9025-z

Hoyer, L.L., and Cota, E. 2016. Candida albicans Agglutinin-Like Sequence (Als) Family Vignettes: A Review of Als Protein Structure and Func-tion. Front Microbiol., 7(280), 1-16. doi: 10.3389/fmicb.2016.00280

Ilhan, Z., Ekin, I.H., Koltas, S., Gulaydın, O., Ozturk, C., and Borum, A.E. 2016. Occurrence of fungal agents in mastitis in dairy goats. Journal of Animal and Plant Sciences, 29(3), 4691-4700

Jawetz, E., Melinick, J., and Adelberg, E.A. 2004. Medical Microbiolo-gy.23ed.,Appelton and Lang. Cali-fornia.

Jones, J.E., and Watkin, G.H. 1998. Stud-ies on mastitis in sheep at the Royal veterinary college. Proceeding of Sheep Veterinary Society, (pp.83-90), Carmarthen, Wales.

Jonsson, P., Olsson, S.O., Olofson, A.S., Falth, C., Holmberg, O., and Funke, H. 1991. Bacteriological investiga-tions of clinical mastitis in heifers in Sweden. J Dairy Res., 58(2), 179-185.

Junaidu, A.U., Salihu, M.D., Tambuwala, F.M., Magaji, A.A., and Jaafaru, S. 2011. Prevalence of mastitis in lac-tating cows in some selected com-mercial dairy farms in Sokoto Me-tropolis. Pelagia Adv. Appl. Sci. Res., 2(2), 290-294. ISSN: 0976-8610

Kano, R., Hattori, Y., Okuzumi, K., Miya-zaki, Y., Yamauchi, R., Koie, H., Watari, T., and Hasegawa, A. 2002. Detection and Identification of the Candida species by 25S Ribo-somal DNA Analysis in the Urine of Candidal Cystitis. Journal of Veterinary Medical Science, 64(2), 115-117 DOI

Katamoto, H., and Shimada, Y. 1990. In-tra-Arterial And Intramammary In-jection Of Miconazole For Bovine Mastitis Caused By Aspergillus Fumigatus. Br. Vet. J., 146, 354-357.

Kivaria, F.M., and Noordhuizen, J. 2006. A retrospective study of the aetiol-ogy and temporal distribution of bovine clinical mastitis in small-holder dairy herds in the Dar es Sa-laam region of Tanzania. The Vet-erinary Journal, 173(3), 617-22 DOI: 10.1016/j.tvjl.2006.01.008

Koç, N. 2003. Antifungal resistance in our country. 3. National Fungal Diseas-es and Clinical Micology Congress (27-30 May, 2003) Congress Book. Bornova, Izmir, Turkey, pp: 285-300

Kotb, E.E.Z., Seeda, A.M., and Fadel, M.A. 2013. Laboratory and Ultrasonographic Diagnosis of Mastitis in Buffaloes Egypt. J. Vet. Sci., 44(1), 69-80.

DOI: 10.21608/EJVS.2013.330

Krukowski, H., Tietze, M., Majewski, T., and Rozanski, P. 2000. Survey of yeast mastitis in dairy herds of small-type farms in the Lublin re-gion, Poland. Mycopathologia, 150(1), 5-7.


Krukowski, H., Lisowski, A., Rózański, P., and Skórka, A. 2006. Yeasts and algae isolated from cows with mas-titis in the South eastern part of Po-land. Pol. J. Vet. Sci., 9:181-184

Ksouri, S., Djebir, S., Hadef, Y., and Benakhla, A. 2015. Survey of bo-vine mycotic mastitis in different mammary gland statuses in two north-eastern regions of Algeria. Mycopathologia, 179(3-4), 327-331. DOI: 10.1007/ s11046-014-9845-2

Kumar, P., and Thakur, D. K. 2000. Fungal mastitis in buffaloes and its treat-ment. Journal of Research, Birsa Agricultural University. 12(2), 291-292

Lassa, H., and Malinowski, E. 2007. Re-sistance Of Yeasts And Algae Iso-lated From Cow Mastitic Milk To Antimicrobial Agents. Bull Vet Inst Pulawy, 51, 575-578

Loftsgard, G., and Lindquist, K. 1960. Bo-vine mycotic mastitis. Acta Vet Scand., 1, 201-220.

Luo, G., and Mitchell, T.H. 2002. Rapid identification of pathogenic fungi directly from cultures by using mul-tiplex PCR. Journal of clinical mi-crobiology, 40(8), 2860-2865. DOI: 10.1128/JCM.40.8.2860–2865.2002

Makimura, K., Murayama, S.Y., and Ya-maguchi, H. 1994. Detection of a wide range of medically important fungi by the polymerase chain reac-tion. J Med Microbiol., 40(5), 358-364,. DOI: 10.1099/00222615-40-5-358

Malinowski, E., Lassa, H., Klossowska, A., and Kuzma, K. 2001. Enzymatic activity of yeast species isolated from bovine mastitis. Bulletin of the Veterinary Institute in Pulawy, 45(2), 289-295

Mansourian, A., Boojarpour, N., Ashnagar, S., Momen Beitollahi, J., and Shamshiri, A.R. 2014. The compar-ative study of antifungal activity of Syzygium aromaticum, Punica granatum and nystatin on Candida albicans; an in vitro study. J. Mycol. Med., 24(4), 163-168.

Martindah, E., Sani, Y., dan Noor, S.M. 2009. Penyakit endemis pada sapi perah dan penanggulangannya. Dalam: Santosa KA, Diwyanto K, Toharmat T, penyunting. Profil usaha peternakan sapi perah di In-donesia. Jakarta (Indonesia): LIPI Press.

Mbuk, E. U., Kwaga, J. K. P., Bale, J. O. O., and Umoh, J. U. 2016. Molecu-lar identification of yeasts associat-ed with raw cow milk from peri-urban farms in Kaduna State, Nige-ria. J. Yeast Fungal Res, 7(5), 39-46. DOI: 10.5897/JYFR2016.0172

Mcdonald. 2009. Mastitis in cow. Dairy Cattle Production 342 – 480. A McDonald Campus of McGill Uni-versity. Faculty of Agricultural and Environmental Sciences. Dep. of Animal Science. 1- 12.

McDonald, J.S., Richard, J.L., Anderson, A.J., and Fichtner, R.E. 1980. In vitro antimycotic sensitivity of yeasts isolated from infected bovine mammary glands. American Journal of Veterinary Research, 41(12), 1987-1990. PMID:7212432

Milanov, D., Pruniš, B., Velhner, M., and Bojkovski, J. 2014. Diagnosis of Yeast Mastitis in Dairy Cows. Lucrări Ştiinţifice Medicină Veterinară, XLVII(1), 56-64

Miller, G.Y., Barlet, P.C., Lance, S.E., An-derson J., and Heider, L.E. 1993. Cost of clinical masititis and mastitis prevention in dairy herds. J. Am. Vet. Med. Assoc., 202(8), 1230-1236. PMID:8496076

Mizher, B.M. 2014. Study of the mycotic mastitis in dairy goats in Al-Diwaniya province. Conference: First Scientific conference for Col-lege of Vet.Medicine/Al-Qasim Green University At: College of Vet.Medicine, Al-Qasim Green University, Iraq.

Mukherjee, P., Seshan, K., Leidich, S., Chandra, J., Cole, G., and Ghannoum, M. 2001. Reintroduc-tion of the PLB1 gene into Candida albicans restores virulence in vivo. Microbiology, 147(9), 2585-2597. DOI:10.1099/00221287-147-9-2585

Naglik, J. R., Challacombe, S.J., and Hube, B. 2003. Candida albicans Secreted Aspartyl Proteinases in Virulence and Pathogenesis. Microbiology and Molecular Biology Reviews, 67(3), 400-428.

DOI: 10.1128/MMBR.67.3.400-428.2003

Nailis, H., Kucharíková, S., Řičicová, M., Van Dijck, P., Deforce, D., Nelis, H., and Coenye, T. 2010. Research article Real-time PCR expression profiling of genes encoding poten-tial virulence factors in Candida albicans biofilms: identification of model-dependent and -independent gene expression.l BMC Microbiol-ogy 2010, 10(114), 1-11 doi: 10.1186/1471-2180-10-114

Nasef, M.E.A., and Dawod, R.E. 2016. A Study on Bacterial and Fungal Causes of Subclinical Mastitis in Dairy Cows. Egypt. J. Chem. Envi-ron. Health, 2(2), 425 -438. ISSN: 2536-9164

Noris, M., Casiraghi, F., Todeschini, M., Cravedi, P., Cugini, D., Monteferrante, G., Aiello, S., Cassis, L., Gotti, E., Gaspari, F., Cattaneo, D., Perico, N., and Remuzzi G. 2007. Regulatory T cells and T cell depletion: role of immunosuppressive drugs. Journal of the American Society of Neph-rology, 18(3), 1007-1018. DOI:10.1681/ASN.2006101143

Pachauri, S., Varshney, P., Dash, S.K., and Gupta, M.K. 2013. Involvement of fungal species in bovine mastitis in and around Mathura, India. Vet World 6(7), 393-395. doi:10.5455/vetworld.2013.393-395

Pal, M., and Dave, P. 2016. Cryptococcosis: An Emerging Air-borne Mycosis of Global Concern. Air Water Borne Diseases, 5(1), 1-4.

doi: 10.4172/2167- 7719.1000127

Panelli, S., Brambati, E., Bonacina, C., and Feligini, M. 2014.Updating on the fungal composition in Sar-dinian sheep's milk by culture-independent methods. 81(2), 233- 237.

Perez, V., Corpa, J.M., García, Marín, J.F., Adúriz, J.J., and Jensen, H.E. 1998. Mammary and systemic aspergillosis in dairy sheep. Vet Pathol., 35(4), 235-40.


Peters, R. R., Komaragiri, S., Paape, M. J., and Douglass, L. W. 2000. Evalua-tion of 1.6% Phenol as a Premilking and Postmilking Teat Dip in Pre-venting New Bovine Intramammary Infection. J Dairy Sci., 83(8), 1750–1757. DOI:10.3168/jds.S0022-0302(00)75045-4

Puspasari, E.R., Yanuartono, Hartati, S., Rahardjo, S., Nururrozi, S., dan Indarjulianto, S. 2018. Isolasi dan identifikasi Staphylococcus Epidermidis pada susu sapi PFH penderita mastitis subklinis di Wukirsari, Cangkringan, Sleman, DIY. Jurnal Ilmu-Ilmu Peternakan, 28(2), 121-128.


Quinn, P.J., Markey, B.K., Leonard, F.C., Fitzpatrick, E.S., Fanning, S. and Hartigan, P.J. 2011. Veterinary mi-crobiology and microbial disease. Second Edition, Blackwell Science Ltd, Oxford, UK.

Ranjan, R., Gupta, M. K., and Singh, K. K. 2011. Study of bovine mastitis in different climatic conditions in Jharkhand, India Rajeev Veterinary World, 4(5), 205-208 DOI: 10.5455/vetworld.2011.205-208 •

Rayaz, A., and Darand, B.G. 2013. Present Status, Future Road Map and Diag-nosis of Zoonotic Mycotic Diseases Biomed. Pharmacol. J., 6(2), 467-470.


Reza, V. H., Mehran, F. M., Majid, M. S., and Hamid, M. 2011. Bacterial pathogens of intramammary infec-tions in Azeri buffaloes of Iran and their antibiogram. African Journal of Agricultural Research, 6(11), 2516-2521.

DOI: 10.5897/AJAR10.204

Ribeiro, M.G., Motta, R.G., Paes, A.C., Allendorf, S.D., Salerno, T., Siqueira, A.K., Fernandes, M.C., and Lara, G.H.B. 2008. Peracute bovine mastitis caused by Klebsiella pneumoniae. Arq. Bras. Med. Vet. Zootec, 60(2), 485-488.

Sanchez, A.G., Perez, J.R., Carillo-Munoz, A.J., Anaya, M.C.G., Mendoza, J.H., and Rodriguez, J.M.A. 1996. In vitro antifungal susceptibility testing on veterinary clinical isolates of yeasts. Mikol Lek., 3, 239-242.

Santos, R.C., and Marin, J.M. 2005. Isola-tion of Candida species from Mastitic bovine milk in Brazil. Mycopathologia, 159(2), 251-253. DOI: 10.1007/s11046-004-2229-2

Sartori, L.C.A., Santos, R.C., and Marin, J.M. 2014 Identification of Candida species isolated from cows suffering mastitis in four Brazilian states Arq. Bras. Med. Vet. Zootec., 66(5), 1615-1617.

Şeker, E. 2010. Identification of Candida Species isolated from Bovine mastitic milk and their in vitro he-molytic activity in Western Turkey. Mycopathologia, 169(4), 303-308. doi: 10.1007/s11046-009-9255-z.

Shadkchan, Y., Shemesh, E., Mirelman, D., Miron, T., Rabinkov, A., Wilchek, M., and Osherov, N. 2004. Efficacy of allicin, the reactive molecule of garlic, in inhibiting Aspergillus spp. in vitro, and in a murine model of disseminated aspergillosis . Journal of Antimicrobial Chemotherapy, 53(5), 832-836. DOI: 10.1093/jac/dkh174

Shaheen, M., Tantary, H.A. and Nabi, S.U. 2016. A Treatise on Bovine Masti-tis: Disease and Disease Economics, Etiological Basis, Risk Factors, Impact on Human Health, Thera-peutic Management, Prevention and Control Strategy. J Adv Dairy Res., 4(1), 1-10. doi: 10.4172/2329-888X.1000150

Sheena, A., and Siegler, L. 1995. Candida krusei isolated from a sporadic case of bovine mastitis. Can. Vet. J., 36(6),365-368. PMCID:PMC1686949

Simaria, M.B., and Dholakia, P.M. 1986. Incidence and diagnosis of mycotic mastitis in cattle. Indian. J. of Anim. Sci., 56(10), 995-1000.

Sonmez, M., and Erbas, G. 2017. Isolation and identification of Candida spp. from mastitic cattle milk and de-termination of antifungal suscepti-bilities. Inter J Vet Sci., 6(2), 104-107.

Spanamberg, A., Sanches, E.M.C., Santurio, J.M., and Ferreiro, L. 2009. Mycotic mastitis in ruminants caused by yeasts. Ciência Rural, Santa Maria, 39(1), 282-290.

Spanamberg, A., Wünder, E.A. Jr., Pereira, D.I.B., Argenta, J., Sanches, E.M.C., Valente, P., and Ferreiro, L. 2008. Diversity of yeasts from bovine mastitis in Southern Brazil. Rev Iberoam Micol., 25(3), 154-156. PMID:18785784

Staroniewicz, Z., Włodarczak, A., Florek, M., and Krol, J. 2007. Fungal flora in cows with mastitis and its sus-ceptibility to antimycotics. Mikologia Lekarska, 14(4), 257–259.

Sudarwanto, M. 1987. Mastitis mikotik pada sapisapi perah di Kabupaten Bogor, Sukabumi dan Cianjur Jawa Barat. Penyakit Hewan XIX (34)II, 70-73.

Sukumar, K., and James, P.C. 2012. Inci-dence of Fungal Mastitis in Cattle. Tamilnadu J. Veterinary & Animal Sciences, 8(6), 356 - 359

Tarfarosh, M.A., and Purohit, S.K. 2008. Isolation of Candida spp. from Mastitic cows and Milkers. Acta Vet. Scand., 3(2), 14-18.

Thompson, K.G., di Menna, M.E., Carter, M.E., and Carman, M.G. 1978. Mycotic mastitis in two cows. New Zealand Veterinary Journal, 26(7), 176-177.

Trisunuwati, P., dan Setyowati, E. 2017. Potensi perasan Daun Binahong (Anredera cordifolia) sebagai antibakterial pada kultur media bakteri Staphylococcus aureus dan Esherichia coli penyebab mastitis klinis penyebab mastitis Sapi Perah. Jurnal Ilmu-Ilmu Peternakan, 27 (1), 18-27.


Van Damme, D.M. 1983. Use of miconazole in treatment for bovine mastitis. Veterinary medicine. Small Animal Clinician, 78, 1425-1427

Van Veen, H.S., and Kremer, W.D. 1992. Mycotic mastitis in cattle. Tijdschr Diergeneeskd, 117(14), 414-416.

Wawron, W., and Krzyzanowsk,i J. 2002. Use of clotrimasol and nystatin in the treatment of mycotic mastitis in cows. Medycyna weterynaryjna, 58(10), 774-776

Wawron, W., Bochniarz, M., and Piech, T. 2010. Yeast Mastitis in Dairy Cows in the Middle – Eastern part of Po-land. Bulletin Veterinary Institute Pulawy, 54, 201-204.

Wellenberg, G.J ., van der Poel, W.H. M., and Van Oirschot, J.T. 2002. Viral infections and bovine mastitis: A review. Veterinary Microbiology, 88(1), 27-45 DOI: 10.1016/S0378-1135(02)00098-6

Williamson, J.H., and Di Menna, M.E. 2007. Fungi isolated from bovine udders, and their possible sources. NZ Vet J., 55(4), 188-190. DOI:10.1080/00480169.2007.36766

Winn, C.W., Allen, D.S., Janda, M.W., Koneman, W.E., Procop, W.G., Schreckenberger, C.P., and Woods, G.L. 2006. Diagnostic Microbiolo-gy. 6thed . Lippincott Williams and Wilkins Company

Yang, Y. 2003. Virulence factors of Can-dida species. J. Microbiol. Immunol. Infect., 36(4), 223- 228. PMID:14723249

Yassein, S.N., Khalaf, J.M., Samaka, H. 2016. Diagnosis of Cryptococcus neoformans from the milk of goat using Multiplex PCR as diagnostic tool. MRVSA, 5(2), 50-57.

Zhou, Y., Ren, Y., Fan, C., Shao, H., Zhang, Z., Mao, W., Wei, C., Ni, H., Zhu, Z., Hou, X., Piao, F., and Cui, Y. 2013. Survey of mycotic mastitis in dairy cows from Heilongjiang Province, China. Trop Anim Health Prod. DOI 10.1007/s11250-013-0419-y



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