PENGARUH PEMBERIAN LEV AMISOL PRA VAKSINASI AVIAN INFLUENZA (Al) TERHADAP RESPON KEBAL AYAM PETELUR
Abstract
Success of vaccination to certain diseases depends of immune response condition. One of drug that can act as immunomodulator is levamisol. The purpose of the reseach was to find out effect  of levamisol  pre AI vaccination  to immune  response  of layer. The research  used  experimental  method  and was based  on Randomized  Completely  Design. One  hundred  and fifty  Days  Old  Chicks  (DOC)  were  divided  into  three  goups  of treatments.  First goup was without levamisole  (control goup).The  second  and third goup were  given  levamisol  at  1  mg/50  kg  body  weight  respetively  for  three  and  six  days, respectively.   Lymphocyte   cell  was  evaluated   between  two  to  five  weeks  after  Al vaccination.  Leucocyte  cells  like monocyte  and  neutrophyl  (heterophyl)  were  examined two days after Al vaccination.
Result  of the research  showed  that levamisole  treatment  pre  AI  vaccination  can highly  significant  increase  non specific immune  response  with  remarkable  increase  in monocyte  cells.  But its effect to total of neutrophyle  cells did not significant.  Levamisole treatment  pre  Al  vaccination  Al  can also  highly  significant  increase  celluler  specific immune response  indicating  by a remarkable  increase  in lymphocyte  cells. Based  of the result,  it  is  concluded  to  necessarily  use  levamisole  pre  Al  vaccination  to  increase immune response  in chickens  against Al natural  infection  (JIIPB  2009 Vol 19 No 1:  10-19)
Keywords  :  levamisole,  vaccination,  immune response,  layer
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